The lower levels of RANTES/CCL5 could be explained by the CD8+ T cells reduction [43–45] and thrombocytopaenia [8, 10, 11, 44–46] observed during vivax malaria. A study carried out with children infected with P. falciparum observed an association between thrombocytopaenia and lower RANTES plasma levels [47]. This evidence concerns the gene CCL5 and Thrombocytopenia.