Among patients with genotype 1b chronic hepatitis C receiving TVR with Peg-IFN α/RBV (TVR-based triple therapy), the SVR rate of patients with the IL28B rs8099917 TT allele was significantly higher than the SVR rate of patients with the IL28B TG/GG allele [7]. The gene discussed is IFNL3; the disease is chronic hepatitis C virus infection.