The MPST was significant in four insulin response studies of skeletal muscles with the smallest U-score of 0.86% (study 4), and the significant differential expression was also observed in four diabetes studies of adipose, arteries, blood and the liver (study 1, 2, 4 and 7) with the smallest U-score of 0.20% (study 4). The gene discussed is INS; the disease is diabetes mellitus.