No significant correlations were found between plasma IL-22 levels and IL22+Th1 (Fig. 5G; P = 0.6444, R = 0.1100) or IL22+Th17 cells (Fig. 5H; P = 0.9749, R = −0.0075), between plasma IL-17 level and total circulating Th17 cells (Fig. 5I; P = 0.7241, R = 0.0842), or between plasma IFN-γ level and total circulating Th1 cells (Fig. 5J; P = 0.7840, R = −0.0654) in non-response RA patient. This evidence concerns the gene IL22 and rheumatoid arthritis.