ESR1 and breast cancer: A separate pathway over-representation analysis for genes annotated to SNPs that were associated with height or post-menopausal breast cancer risk also retrieved the Ihh pathway as the most overrepresented pathway (STK36, IHH) (p-value = 1.13 × 10−4), as well as some distinct pathways, such as the ERBB4 signalling pathway (ESR1, TNRC6B) (p-value = 9.10 × 10−3) and androgen receptor pathway (ESR1, ZMIZ1) (p-value = 9.02 × 10−3) (Table 2).