SLC5A5 and cancer: Several researchers have reported the possible use of radioiodide for the treatment of cancers by forced expression of NIS in tumors of several origins, such as in prostate cancer (94,95), hepatoma (96), glioma (97), neuroendocrine tumor cells (98), head and neck squamous cell carcinoma (99), colon cancer (100,101), pancreatic tumors (102), and in ovarian tumor xenografts (103).