IL2 and neoplasm: In pilot experiments, titration experiments using radiation doses of 5 and 8 Gy and MVA-MUC1-IL-2 vaccine doses of 105, 106 and 107 PFU showed that the combination of 8 Gy tumor irradiation with 107 PFU MVA-MUC1-IL-2 was the most effective for the treatment of Renca-MUC1 s.c. tumors (Additional file 1: Figure S1 and Additional file 2: Figure S2).