IFNG and Crohn ileitis: Given that upon peroral T. gondii infection the small, but not large intestinal tract has been described as exclusive intestinal predilection site of inflammation so far [13], we unexpectedly observed elevated IFN-γ secretion even in supernatants of colonic ex vivo biopsies at day 7 post ileitis induction in either mice (p < 0.001; Fig. 6b).