IFNG and Crohn ileitis: Interestingly, IFN-γ and nitric oxide secretion increased in ex vivo biopsies taken from liver and kidney until day 7 following ileitis induction in both P. aeruginosa infected and uninfected hma mice (p < 0.05 to 0.001; Fig. 7), whereas nitric oxide levels were slightly lower in the liver of the latter as compared to the former (p < 0.05; Fig. 7a).