PROM1 and Ewing sarcoma: They found that TARBP2 (TAR RNA-binding protein 2), which forms part of the Dicer-1 complex, was suppressed in CD133+ Ewing sarcoma cells as well as hpMSCEWS-FLI-1, and enoxacin, which augments TARBP2 function, inhibited tumor growth through the restoration of miRNA maturation [81].