TRAF2 and neoplasm: Originally, miR-502 was reported to be a tumour-related miRNA that inhibited several tumour-associated proteins, such as histone methyltransferase SET8, TP53 codon 72 polymorphism, tumour necrosis factor receptor associated factor 2 (TRAF2) and was involved in many processes, including apoptosis, proliferation, motility and invasiveness [23–25].