This group reported the simultaneous expression of Vα2.3 together with the Vβ22 chain on highly clonal BAL-isolated CD4+ T-cells on a cohort of DRB1*03+ sarcoidosis patients and molecular modelling indicated a specific T-cell receptor–HLA- DRB1*03+- vimentin peptide (Vim429-443) interaction [32]. The gene discussed is VIM; the disease is sarcoidosis.