MARK2 and neoplasm: Aurora kinases are highly conserved serine/threonine kinases.3 The canonical function of Aurora kinases is regulating centrosome duplication and separation by promoting mitotic spindle assembly.4 A large body of research indicates that Aurora kinase A (AURKA) overexpresses in a variety of tumours and endows them with uncontrolled mitosis.4, 5 Consistent with previous studies, along with others, we have uncovered that AURKA dysregulation is associated with tumour metastasis and chemotherapeutic resistance.