The role of both genes are poorly understood in melanoma metastases, however, FGF13, which is a special type of FGFs, is not only associated with signaling processes but also has a role in microtubule stabilization and the regulation of neuronal polarization and migration.52 Hence, FGF13 may present a new driver of melanoma metastasis. The gene discussed is FGF13; the disease is melanoma.