As shown in Fig. 2, serum levels of E-selectin and ICAM-1 and lung W/D ratio increased, serum NO concentration decreased significantly in Saline rats either among those suffering DCS (shown as Figure A1–D1) or in the group as a whole (shown as Figure A2–D2) when compared with Normal rats (P < 0.01). Here, ICAM1 is linked to Dorfman-Chanarin disease.