The resistance-promoting effect of Cav1-deficient HS5(−) fibroblasts was further analyzed by determining the degree of apoptosis (SubG1 fraction) after radiation in PC3 (+/−Cav1) and Cav1-deficient LNCaP prostate cancer cells in the presence of HS5 SN (Fig. 7C,D). This evidence concerns the gene CAV1 and prostate cancer.