miR-141 suppression of PCa clonal and tumour growth was associated with inhibition of cell proliferation as evidenced by reduced 5-ethynyl-2′-deoxyuridine (EdU) incorporation in miR-141-overexpressing cells (Supplementary Fig. 2c–e) and reduced Ki-67+ cells in miR-141-overexpressing tumours (Supplementary Fig. 2f). This evidence concerns the gene MKI67 and posterior cortical atrophy.