PRPF8 and Zika virus infectious disease: In summary, ZIKV infection modulates pathways such as RNA processing (DDX6, PCBP2), miRNA biogenesis (DGCR8, XPO1), translational initiation regulation (eIF3c), and proteins such as splicing factors (SFPQ, PRP8), ribosomal proteins (RPS6KA5, RPL28), innate immune response (TLR4) and neuronal development (NEUROD1, SATB2).