ADA and hyperinsulinemic hypoglycemia, familial, 4: Moreover, iPSC differentiation is a potential source of tissue-resident macrophages for cell therapy, as has recently been shown in the mouse with the use of murine pluripotent stem cell-derived Myb−/− alveolar-like macrophages as a cell source for treating a mouse model of adenosine deaminase deficiency (ADA−/−) (Litvack et al., 2016).