As shown in figure 1, the prevalence of pre-diabetes and T2DM in women were increased in sequence from the bottom to the top tertiles of the ApoB/ApoA-I ratio (for pre-diabetes: T1:16.5%, T2:19.8%, T3:25.5%, p=0.014; for diabetes, T1:6.2%, T2:22.2%, T3:32.1%, p<0.001). The gene discussed is APOA1; the disease is type 2 diabetes mellitus.