Furthermore, corresponding to the decrease in 99mTc-sestamibi defect size, the uptake of 99mTc-Annexin V in the infarcted area was absent 4 d after acute myocardial infarction, which indicates that in parts of the area at risk, reversible myocardial damage rather than necrosis is present in cardiomyocytes [30]. This evidence concerns the gene ANXA5 and myocardial infarction.