In the study of Lampl et al., four of five patients with Alzheimer dementia (AD) showed multifocal cortical 99mTc-Annexin V uptake, whereas patients with non-AD dementia and non-diseased healthy age-matched controls had normal SPECT image, which suggested the feasibility of 99mTc-Annexin V for imaging AD. The gene discussed is ANXA5; the disease is Alzheimer disease.