MYC, miR-17-5p, and miR-20a are up-regulated by CCAT2 through transcription factor 7 like 2 (TCF7L2)-mediated transcriptional regulation and the interaction between CCAT2 and TCF7L2 results in an enhancement in WNT signaling activity, which promotes tumor growth and metastasis in CRC [7]. The gene discussed is MYC; the disease is neoplasm.