Ubiquitin-like plant homeodomain and really interesting new gene finger domain-containing protein 1 (UHRF1) protein associated transcript interacts with and stabilizes the epigenetic factor UHRF1 by interfering with its β-transducin repeat-containing protein-mediated ubiquitination to play a critical role in the survival and tumorigenicity of CRC [109]. This evidence concerns the gene UHRF1 and colorectal carcinoma.