Interestingly, a previous report of STIM1 knockdown did not alter the expression or phosphorylation of MAPK or extracellular signal-regulated kinase (ERK) in gastric cancer [15], indicating that STIM1 regulates different pathways in different cancer types, which may account for the different roles of STIM1 in different cancers. Here, STIM1 is linked to gastric cancer.