SNCA and synucleinopathy: Our deposition of PARK4 blood RNA-seq data at the ENA database aims to drive this effort, ensuring that PD risk, which is triggered by the genetically defined synucleinopathy of PARK4 in the Turkish pedigree and mirrored by specific pathways and molecular biomarkers, can now be compared with diverse ongoing data collections in individuals with manifest PD, usually without a family history and with multifactorial pathogenesis (Scherzer et al., 2007; Marek et al., 2011; Santiago and Potashkin, 2015).