To be specific, the analysis combined with the clinical data (Table 2-3) indicated that the expression level of ADAMTSL4 showed negative correlations with the nasopharyngeal carcinoma lymph node metastasis (P = 0.002), distant metastasis (P = 0.020) and clinical staging (P = 0.006). This evidence concerns the gene ADAMTSL4 and nasopharyngeal carcinoma.