According to our previous ELISA analysis, on the serum ADAMTSL4 and TXN levels in NPC patients without any therapy prior to the diagnosis, it was found that the serum ADAMTSL4 levels in non-metastasis NPC patients were higher than those in metastasis NPC patients, whereas the serum TXN levels in non-metastasis and metastasis NPC patients were not significantly different. This evidence concerns the gene ADAMTSL4 and nasopharyngeal carcinoma.