Similar data were obtained when treating mice bearing a single wild-type SQD9 tumor with vehicle and MCT1 inhibitor AR-C155858 (Figure 5A and Supplementary Video 2; pictures of a same mouse imaged on different days are shown) and AZD3965 (Figure 5B and Supplementary Video 3; pictures of a same mouse imaged on different days are shown), thus confirming that [18F]-FLac can be used to image MCT1-dependent lactate uptake inhibition in vivo. The gene discussed is SLC16A1; the disease is neoplasm.