These phosphorylated substrates translocate to the nucleus to regulate the transcription of several target genes—including cancer-associated genes such as snail, slug, and zinc finger E-box-binding homeobox (ZEB)1/2—which are known to promote epithelial-mesenchymal transition (EMT), metastasis, cancer stem cell maintenance, and angiogenesis [5,6]. Here, SNAI1 is linked to cancer.