LEP and obesity due to melanocortin 4 receptor deficiency: The human LEP gene (leptin; synonyms: obesity factor with acronym OB) contains a candidate SNP marker (rs201381696) of obesity (reducing this gene’s expression) as well as candidate SNP markers (rs200487063 and rs34104384) of obesity-induced hypertension caused by overexpression of this gene as we have predicted in silico and verified in vitro in our previous work [66] (Table 4).