The human IL1B gene (interleukin 1β) has an SNP marker (rs1143627) of a wide variety of human diseases such as Graves’ disease [77], major recurrent depression [78], greater body fat in older men [79], non–small cell lung cancer [80], hepatocellular carcinoma [81], gastric cancer [82], gastric ulcer, and chronic gastritis [83] (Table 1). This evidence concerns the gene IL1B and major depressive disorder.