Activated platelets also secrete transforming growth factor β (TGF-β) (Assoian and Sporn, 1986) and platelet-derived growth factor (PDGF) (Kong et al., 2008) from α-granules in response to tumor cell stimulation, inducing EMT (Assoian and Sporn, 1983; Radisky and LaBarge, 2008; Labelle et al., 2011; Yu et al., 2013; Leblanc and Peyruchaud, 2016). The gene discussed is TGFB1; the disease is neoplasm.