BIRC5 and neoplasm: 2,5‐dimethyl celecoxib (DMC), is a non‐cyclooxygenase‐2 inhibitor analog of celecoxib that can mimic the anti‐tumor effect of celexib.163 Ferrario et al. discovered that DMC enhanced PDT tumoricidal responsiveness without altering COX‐2 activity.152 DMC and celecoxib reduced pro‐survival protein survivin expression induced by PDT, enhanced the endoplasmic reticulum stress response of PDT and increased apoptosis and cytotoxicity in BA cells.