TP53 and colorectal adenocarcinoma: By others, the NFY TF family has been previously studied as a mediator of tissue invasion in granulocytes via regulation of cell-to-cell adhesion through induction of CD34 [39, 40], has known roles in angiogenesis [41], is negatively regulated by p53 [42], and has been implicated in colorectal adenocarcinoma formation and metastasis [43].