GNPTAB and Merkel cell skin cancer: We next generated a reliable list of genes upregulated during MCC differentiation based on differential expression (p adjusted for multiple testing < 0.05) between pairs of conditions exhibiting the greatest change in MCC number (Fig 1B and 1E: dbm vs. Notch-icd, Notch-icd + Multicilin vs. Notch-icd, and dbm vs dbm + dnMulticilin).