To examine this possibility, we immunised an HLA-A2 human volunteer with the live attenuated yellow fever vaccine YFV-17D, took a peripheral blood sample 15 days post-vaccination, and used dextramer staining and single-cell RNAseq to recover paired TCRαβ sequences from CD8+ T cells specific for the immunodominant epitope HLA-A02:01/LLWNGPMAV (see Methods; data provided in S1 Dataset). This evidence concerns the gene CD8A and viral infectious disease.