Figure 3d shows that 48 h after the virus infection in 3T3-L1 cells, we were able to detect the expression of HA-tagged exogenous TCF7L2 or TCF7L2DN. Figures 3e and g confirm that TCF7L2DN expression increased 3T3-L1 differentiation while wild type TCF7L2 expression reduced 3T3-L1 differentiation. The opposite effects of Ad-TCF7L2 and Ad-TCF7L2DN infection on mRNA levels of a battery of adipogenic genes in differentiated 3T3-L1 cells are shown in Figure 3h. Here, TCF7L2 is linked to viral infectious disease.