In an attempt to validate these findings in independent cohorts and address whether AURKA played a role in specific molecular subsets of bladder cancer, we investigated the relationships between AURKA and NNMT expression levels and outcomes in two genomically characterized cohorts (The Cancer Genome Atlas, TCGA; The University of Texas MD Anderson Cancer Center, MDA) comprising 128 and 142 bladder samples, respectively. This evidence concerns the gene AURKA and urinary bladder cancer.