The results of mRNA expression from real-time PCR showed that CTNNB1 mutated adenoma had similar density of CYP11B2 expression as WT patients; however, both groups of adenoma had less CYP11B2 expression than those with KCNJ5 mutations (all p < 0.01; Fig. 2a). Here, CYP11B2 is linked to adenoma.