In support of this possibility we found that, unlike FGF2, effects of the acidic FGF1 (pI≈6) on tumour cell proliferation were not affected by α3(V) ablation (Fig. 7a) and that FGF1 did not bind α3(V)-NTD or GPC1 in immunoprecipitations. Here, FGF1 is linked to neoplasm.