CD8A and non-small cell lung carcinoma: Specifically, the frequencies of the CD4+ Tn (p = 0.031) and Tcm cells (p = 0.0032) were greater than those of the CD8+ T cells in the blood of the NSCLC patients; the proportion of the CD4+ Tcm was greater than that of the CD8+ Tcm cells both in blood and lymph node from healthy donor and NSCLC patients (Fig. 1d).