CD8A and non-small cell lung carcinoma: In addition, the fraction of the CD8+ Teff cells was higher than that of the CD4+ Teffs in the NSCLC-PBMC (p = 0.0003), HD-PBMCs (p = 0.0004), Normal-Ly (p = 0.0181), and NSCLC-Ly (p = 0.003) (Fig. 1d).