Interestingly, Evers et al. demonstrated that in patients with neurofibromatosis type-2 meningiomas, skull base tumours have higher growth rates compared with convexity and other locations whereas Hashimoto et al. demonstrated that in non-NF2 related meningiomas, tumour doubling-time was significantly lower in non-skull base tumours [5, 7]. This evidence concerns the gene NF2 and meningioma.