ACE2 and Hepatic fibrosis: Accordingly, both ACE inhibitors and AT1 antagonists protect from fatty liver and fibrosis [18], recombinant ACE2 has beneficial effects on hepatic fibrosis in mice [19], and during the preparation of this manuscript, Cao and collaborators [20] showed that ACE2/Ang-(1–7)/Mas axis may reduce liver lipid accumulation.