In contrast, interpreting the data using the V3 model suggests that CD8+ T cells that enter the tumor microenvironment are 12 times more likely to proliferate than die when antigen is sparse (log ratio kp3a− / kd5− = 1.1 ± 1.5) and, in an antigen-dense environment, are initially 4 times more likely to die than proliferate (log ratio kp3a− / kd5− = −0.63 ± 2.0). Here, CD8A is linked to neoplasm.