STAT3 is one of the best studied oncogenic signaling nodes, and it exerts enormous influence on tumor growth properties, including the support of stemness in diverse cancer types including those of breast, prostate, and brain (Dasgupta et al., 2009; Marotta et al., 2011; Schroeder et al., 2014; Wang et al., 2009). Here, STAT3 is linked to neoplasm.