Treatment of mice with cordycepin significantly suppressed tumor growth (Figure 6A, 6B) and upregulated CAV1 and JNK phosphorylation, whereas it inhibited the phosphorylation of Foxo3a and only slightly increased the total Foxo3a protein level as compared to untreated control (Figure 6C, 6D). This evidence concerns the gene MAPK8 and neoplasm.