Of the potential candidate genes, the paternally expressed growth promoter insulin like growth factor 2 (IGF2) and the maternally expressed candidate tumor suppressor genes CDKN1C and H19, have been most consistently implicated in imprinting disorders, such as Beckwith-Wiedemann Syndrome and Silver-Russell Syndrome [21]. The gene discussed is IGF2; the disease is Beckwith-Wiedemann syndrome.