YAP1 and obesity due to melanocortin 4 receptor deficiency: Elevated YAP activity/expression strongly correlated with tumor histological differentiation in pancreatic cancer tissue (χ2 = 5.294, p = 0.048), however, YAP has no statistical criteria with age, sex, smoking, drinking, obesity, impaired glucose tolerance, diabetes, chronic pancreatitis and clinical stage (Table 1).