Our study demonstrated that SJAMP could obviously decrease Survivin and YAP mRNA level and raise the apoptosis factor caspase-9 mRNA level, which indicated that SJAMP could excite the mitochondrion apoptosis pathway and promote the pancreatic cancer cell apoptosis by inhibiting the expression of Survivin and prompting the level of Caspase-9. Here, YAP1 is linked to familial pancreatic carcinoma.