LRRK2 and immune system disorder: Of the 6 SNPs previously reported to be associated with immune diseases, only rs2638272 in the LRRK2 gene was observed to be associated with SLE in the first patient population (rs2638272G with P = 1.14 × 10−2; OR 1.24 (95% CI 1.04–1.48) (Table 1).