We observed that LRRK2 mRNA expression was significantly up-regulated in SLE PBMC compared with normal donor controls (mean + SD normalized fluorescence intensity 2893.56 + 1162.33 among 61 SLE patients versus 1886.76 + 535.16 among 20 normal donor controls; p = 1.42 × 10−6) (Figure 2). The gene discussed is LRRK2; the disease is systemic lupus erythematosus.