ADAMTS5 and neoplasm: In IDC II and IDC II–III, Fibulin-2 was in the periductal and perivascular stroma (Figure 4E) or in some well delimited cells of the tumor cells masses (Figure 4G); whereas ADAMTS-5 showed a faint immunoreactivity paralleled to that of Fibulin-2 (Figure 4F) or diffusely presented in masses of epithelial cells (Figure 4H).