As shown in Supplementary Table 2 and Figure 4, these genes participated in multiple pathways in cancer (PATH:05200), including PI3K-Akt signaling pathway, Focal adhesion, MAPK signaling pathway, Ras signaling pathway, VEGF signaling pathway, TGF-β signaling pathway, TNF signaling pathway, Cell adhesion molecules (CAMs), Tight junction, Wnt signaling pathway, Notch signaling pathway, Hedgehog signaling pathway, mTOR signaling pathway, et al.. The gene discussed is MTOR; the disease is cancer.