As shown in Supplementary Table 2 and Figure 4, these genes participated in multiple pathways in cancer (PATH:05200), including PI3K-Akt signaling pathway, Focal adhesion, MAPK signaling pathway, Ras signaling pathway, VEGF signaling pathway, TGF-β signaling pathway, TNF signaling pathway, Cell adhesion molecules (CAMs), Tight junction, Wnt signaling pathway, Notch signaling pathway, Hedgehog signaling pathway, mTOR signaling pathway, et al.. This evidence concerns the gene TGFB1 and cancer.