At the same time, FIH(–) showed correlation with none tumor encapsulation (p = 0.018), vascular invasion (p = 0.048), higher TNM stage (p = 0.003), higher BCLC stage (p = 0.015), higher MVD (p = 0.009) and higher Ki-67 LI (p = 0.020). The gene discussed is MKI67; the disease is neoplasm.