Univariate analysis of prognostic factors showed that PHD3 expression (p =0.009), FIH expression (p = 0.001), tumor number (p = 0.002), tumor encapsulation (p = 0.002), vascular invasion (p < 0.001), TNM stage (p < 0.001) and BCLC stage (p < 0.001) had significant prognostic influences on DFS (Table 2); regarding OS, FIH expression (p < 0.001), tumor size (p = 0.030), tumor number (p = 0.013), tumor encapsulation (p = 0.023), vascular invasion (p = 0.006), TNM stage (p = 0.001) and BCLC stage (p = 0.001) were the risk factors (Table 3). The gene discussed is EGLN3; the disease is neoplasm.