Despite its low specificity, CRP has unique characteristics that are advantageousfor its use in critically ill patients.(22) These include the fact that CRP is apparently littleaffected by the use of systemic corticosteroids; if the cause of its elevationis infectious, its concentrations are not changed by immunosuppression(including in critically ill adult patients with sepsis and neutropenia, forexample). Here, CRP is linked to Decreased total neutrophil count.