IL6 and Sepsis: IL-6 serum levels are higher in childrendiagnosed with sepsis than in patients with noninfectious systemic inflammationonly,(43,44) and its diagnostic accuracyincreases when combined with other diagnostic biomarkers, including CRP, forexample.(43)Furthermore, among children with sepsis, an increase in IL-6 level is associatedwith more severe cases,(45)and its use in clinical practice can provide a good predictor of severesepsis.