Assessment of PCT, CRP, TNF-alpha,IL-1b, IL-8 and TNF-receptor II values in the rapid and earlydiagnosis of infection in patients with acute lymphocyticleukemia and febrile neutropenia and differentiation betweenbacterial and viral infection  The SL of biomarkers wereassessed on admission and for 7 consecutive days  PCT SLwere significantly different between bacterial and non-bacterialepisodes, with 94% sensitivity and 96.5% specificity. Here, CALCA is linked to viral infectious disease.