18 of 90 episodes of febrileneutropenia were classified as bacteremia/sepsis  Atdays 1 and 2, CRP and other biomarkers had low to moderatediagnostic accuracy for sepsis with no significant differencebetween biomarkers  The diagnostic accuracy of CRP waslower than that of IL-6 and PCT in severe sepsis. The gene discussed is CALCA; the disease is bacterial infectious disease with sepsis.