HMGB1 and glycogen storage disease VI: Recently, it was reportedthat HMGB1 can potentiate the release of the adhesion molecules ICAM-1, VCAM-1 andE-selectin on endothelial membranes, which can be associated with endothelialdysfunction.(19) The broadroles of IL-33 and ST2 in numerous diseases, but mainly in the pathophysiology ofcardiovascular diseases, have been demonstrated.(20) We wanted to evaluate whether HMGB1 and solubleST2 can predict microvascular endothelial function as measured by RH-PAT in septicpatients.